一直生活在姐姐成功的阴影下的克莱奥（罗温·布兰查德 Rowan Blanchard 饰）在科研试验过程中不小心制出了隐形药剂，把姐姐变成了隐形人。经过了一系列艰难险阻，遭到忽视的克莱奥能成功将平日如影随形的姐姐变回来吗？姐妹俩又将如何处置彼此之间的尴尬关系呢？面对暗恋的男生卡特，又能否顺利的告白呢？...

Loki joins forces with Bart Simpson to fight against his toughest opponents in Springfield after he is banished from Asgard yet again....